Role of Azoles in Antifungal Therapy
نویسندگان
چکیده
منابع مشابه
Antifungal azoles: old and new.
Management of fungal infections is complex with increasing choice of antifungals. Mortality and morbidity are significant despite treatment. Azoles are commonly used compounds which inhibit fungal lanosterol 14 demethylase, thereby depleting ergosterol in the fungal cell membrane with the accumulation of lanosterol precursors. Imidazoles (miconazole, ketoconazole, clotrimazole) are used in topi...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 1996
ISSN: 1537-6591,1058-4838
DOI: 10.1093/clinids/22.supplement_2.s148